Welcome to Irene, South Dakota. We are a small hometown community with a population of 441, organized in 1893. Irene is located in 3 counties (Clay, Turner, and Yankton).
Irene is located on SD Highway 46 southwest of Sioux Falls by 55 miles and northeast of Yankton by approximately 30 miles.
In 2018 Irene celebrated it's 125th Anniversary in June. There was a parade, street dance, beverage tent, food vendors, kids' activities, volleyball, basketball and golf tournaments, fireworks, a museum, and the Irene Rodeo.
It was a great success and good times were had by all. Many alumni and past residents visited and reminisced about the past.